Profile

Affiliate Professor.
Bacterial adaptation mechanisms. Loves the feeling of being on the road.
Publications
Mahmud, AKM Firoj; Nandi, Soumyadeep; Fallman, Maria ProkSeq for complete analysis of RNA-seq data from prokaryotes Journal Article bioRxiv, 2020. @article{mahmud2020prokseq, title = {ProkSeq for complete analysis of RNA-seq data from prokaryotes}, author = {AKM Firoj Mahmud and Soumyadeep Nandi and Maria Fallman}, year = {2020}, date = {2020-01-01}, journal = {bioRxiv}, publisher = {Cold Spring Harbor Laboratory}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Taheri, Nayyer; Fällman, Maria; Wai, Sun Nyunt; Fahlgren, Anna Accumulation of virulence-associated proteins in Campylobacter jejuni outer membrane vesicles at human body temperature Journal Article Journal of proteomics, 195 , pp. 33–40, 2019. @article{taheri2019accumulation, title = {Accumulation of virulence-associated proteins in Campylobacter jejuni outer membrane vesicles at human body temperature}, author = {Nayyer Taheri and Maria Fällman and Sun Nyunt Wai and Anna Fahlgren}, year = {2019}, date = {2019-01-01}, journal = {Journal of proteomics}, volume = {195}, pages = {33--40}, publisher = {Elsevier}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Taheri, Nayyer; Wai, Sun Nyunt; Fällman, Maria; Fahlgren, Anna Campylobacter jejuni outer membrane vesicles activate inflammasome without inducing cell death in immune cells Journal Article 2019. @article{taheri2019campylobacter, title = {Campylobacter jejuni outer membrane vesicles activate inflammasome without inducing cell death in immune cells}, author = {Nayyer Taheri and Sun Nyunt Wai and Maria Fällman and Anna Fahlgren}, year = {2019}, date = {2019-01-01}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Taheri, Nayyer; Mahmud, AKM Firoj; Sandblad, Linda; Fällman, Maria; Wai, Sun Nyunt; Fahlgren, Anna Campylobacter jejuni bile exposure influences outer membrane vesicles protein content and bacterial interaction with epithelial cells Journal Article Scientific reports, 8 (1), pp. 1–14, 2018. @article{taheri2018campylobacter, title = {Campylobacter jejuni bile exposure influences outer membrane vesicles protein content and bacterial interaction with epithelial cells}, author = {Nayyer Taheri and AKM Firoj Mahmud and Linda Sandblad and Maria Fällman and Sun Nyunt Wai and Anna Fahlgren}, year = {2018}, date = {2018-01-01}, journal = {Scientific reports}, volume = {8}, number = {1}, pages = {1--14}, publisher = {Nature Publishing Group}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Erttmann, Saskia F; Härtlova, Anetta; Sloniecka, Marta; Raffi, Faizal AM; Hosseinzadeh, Ava; Edgren, Tomas; Rofougaran, Reza; Resch, Ulrike; Fällman, Maria; Ek, Torben; others, Loss of the DNA damage repair kinase atm impairs inflammasome-dependent anti-bacterial innate immunity Journal Article Immunity, 47 (6), pp. 1210–1211, 2017. @article{erttmann2017loss, title = {Loss of the DNA damage repair kinase atm impairs inflammasome-dependent anti-bacterial innate immunity}, author = {Saskia F Erttmann and Anetta Härtlova and Marta Sloniecka and Faizal AM Raffi and Ava Hosseinzadeh and Tomas Edgren and Reza Rofougaran and Ulrike Resch and Maria Fällman and Torben Ek and others}, year = {2017}, date = {2017-01-01}, journal = {Immunity}, volume = {47}, number = {6}, pages = {1210--1211}, publisher = {Elsevier}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Erttmann, Saskia F; Härtlova, Anetta; Sloniecka, Marta; Raffi, Faizal AM; Hosseinzadeh, Ava; Edgren, Tomas; Rofougaran, Reza; Resch, Ulrike; Fällman, Maria; Ek, Torben; others, Loss of the DNA damage repair kinase ATM impairs inflammasome-dependent anti-bacterial innate immunity Journal Article Immunity, 45 (1), pp. 106–118, 2016. @article{erttmann2016loss, title = {Loss of the DNA damage repair kinase ATM impairs inflammasome-dependent anti-bacterial innate immunity}, author = {Saskia F Erttmann and Anetta Härtlova and Marta Sloniecka and Faizal AM Raffi and Ava Hosseinzadeh and Tomas Edgren and Reza Rofougaran and Ulrike Resch and Maria Fällman and Torben Ek and others}, year = {2016}, date = {2016-01-01}, journal = {Immunity}, volume = {45}, number = {1}, pages = {106--118}, publisher = {Elsevier}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Taheri, Nayyer; Fahlgren, Anna; Fällman, Maria Yersinia pseudotuberculosis blocks neutrophil degranulation Journal Article Infection and immunity, 84 (12), pp. 3369–3378, 2016. @article{taheri2016yersinia, title = {Yersinia pseudotuberculosis blocks neutrophil degranulation}, author = {Nayyer Taheri and Anna Fahlgren and Maria Fällman}, year = {2016}, date = {2016-01-01}, journal = {Infection and immunity}, volume = {84}, number = {12}, pages = {3369--3378}, publisher = {Am Soc Microbiol}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Ekestubbe, Sofie; Bröms, Jeanette E; Edgren, Tomas; Fällman, Maria; Francis, Matthew S; Forsberg, Åke The amino-terminal part of the needle-tip translocator LcrV of Yersinia pseudotuberculosis is required for early targeting of YopH and in vivo virulence Journal Article Frontiers in cellular and infection microbiology, 6 , pp. 175, 2016. @article{ekestubbe2016amino, title = {The amino-terminal part of the needle-tip translocator LcrV of Yersinia pseudotuberculosis is required for early targeting of YopH and in vivo virulence}, author = {Sofie Ekestubbe and Jeanette E Bröms and Tomas Edgren and Maria Fällman and Matthew S Francis and Åke Forsberg}, year = {2016}, date = {2016-01-01}, journal = {Frontiers in cellular and infection microbiology}, volume = {6}, pages = {175}, publisher = {Frontiers}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Avican, Ummehan; Avican, Kemal; Fällman, Maria; Forsberg, Åke Transcriptomic and phenotypic analysis of sufI and tatC mutants of Yersinia pseudotuberculosis Journal Article 2016. @article{avican2016transcriptomic, title = {Transcriptomic and phenotypic analysis of sufI and tatC mutants of Yersinia pseudotuberculosis}, author = {Ummehan Avican and Kemal Avican and Maria Fällman and Åke Forsberg}, year = {2016}, date = {2016-01-01}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Avican, Kemal; Fahlgren, Anna; Huss, Mikael; Heroven, Ann Kathrin; Beckstette, Michael; Dersch, Petra; Fällman, Maria Reprogramming of Yersinia from virulent to persistent mode revealed by complex in vivo RNA-seq analysis Journal Article PLoS Pathog, 11 (1), pp. e1004600, 2015. @article{avican2015reprogramming, title = {Reprogramming of Yersinia from virulent to persistent mode revealed by complex in vivo RNA-seq analysis}, author = {Kemal Avican and Anna Fahlgren and Mikael Huss and Ann Kathrin Heroven and Michael Beckstette and Petra Dersch and Maria Fällman}, year = {2015}, date = {2015-01-01}, journal = {PLoS Pathog}, volume = {11}, number = {1}, pages = {e1004600}, publisher = {Public Library of Science}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Westermark, Linda; Fahlgren, Anna; Fällman, Maria Yersinia pseudotuberculosis efficiently escapes polymorphonuclear neutrophils during early infection Journal Article Infection and immunity, 82 (3), pp. 1181–1191, 2014. @article{westermark2014yersinia, title = {Yersinia pseudotuberculosis efficiently escapes polymorphonuclear neutrophils during early infection}, author = {Linda Westermark and Anna Fahlgren and Maria Fällman}, year = {2014}, date = {2014-01-01}, journal = {Infection and immunity}, volume = {82}, number = {3}, pages = {1181--1191}, publisher = {Am Soc Microbiol}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Fahlgren, Anna; Avican, Kemal; Westermark, Linda; Nordfelth, Roland; Fällman, Maria Colonization of cecum is important for development of persistent infection by Yersinia pseudotuberculosis Journal Article Infection and immunity, 82 (8), pp. 3471–3482, 2014. @article{fahlgren2014colonization, title = {Colonization of cecum is important for development of persistent infection by Yersinia pseudotuberculosis}, author = {Anna Fahlgren and Kemal Avican and Linda Westermark and Roland Nordfelth and Maria Fällman}, year = {2014}, date = {2014-01-01}, journal = {Infection and immunity}, volume = {82}, number = {8}, pages = {3471--3482}, publisher = {Am Soc Microbiol}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Thorslund, Sara E; Ermert, David; Fahlgren, Anna; Erttmann, Saskia F; Nilsson, Kristina; Hosseinzadeh, Ava; Urban, Constantin F; Fällman, Maria Role of YopK in Yersinia pseudotuberculosis resistance against polymorphonuclear leukocyte defense Journal Article Infection and immunity, 81 (1), pp. 11–22, 2013. @article{thorslund2013role, title = {Role of YopK in Yersinia pseudotuberculosis resistance against polymorphonuclear leukocyte defense}, author = {Sara E Thorslund and David Ermert and Anna Fahlgren and Saskia F Erttmann and Kristina Nilsson and Ava Hosseinzadeh and Constantin F Urban and Maria Fällman}, year = {2013}, date = {2013-01-01}, journal = {Infection and immunity}, volume = {81}, number = {1}, pages = {11--22}, publisher = {Am Soc Microbiol}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Costa, Tiago RD; Amer, Ayad AA; Farag, Salah I; Wolf-Watz, Hans; Fällman, Maria; Fahlgren, Anna; Edgren, Tomas; Francis, Matthew S Type III secretion translocon assemblies that attenuate Y ersinia virulence Journal Article Cellular microbiology, 15 (7), pp. 1088–1110, 2013. @article{costa2013type, title = {Type III secretion translocon assemblies that attenuate Y ersinia virulence}, author = {Tiago RD Costa and Ayad AA Amer and Salah I Farag and Hans Wolf-Watz and Maria Fällman and Anna Fahlgren and Tomas Edgren and Matthew S Francis}, year = {2013}, date = {2013-01-01}, journal = {Cellular microbiology}, volume = {15}, number = {7}, pages = {1088--1110}, publisher = {Wiley Online Library}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Lindell, Kristoffer; Fahlgren, Anna; Hjerde, Erik; Willassen, Nils-Peder; Fällman, Maria; Milton, Debra L Lipopolysaccharide O-antigen prevents phagocytosis of Vibrio anguillarum by rainbow trout (Oncorhynchus mykiss) skin epithelial cells Journal Article PLoS One, 7 (5), pp. e37678, 2012. @article{lindell2012lipopolysaccharide, title = {Lipopolysaccharide O-antigen prevents phagocytosis of Vibrio anguillarum by rainbow trout (Oncorhynchus mykiss) skin epithelial cells}, author = {Kristoffer Lindell and Anna Fahlgren and Erik Hjerde and Nils-Peder Willassen and Maria Fällman and Debra L Milton}, year = {2012}, date = {2012-01-01}, journal = {PLoS One}, volume = {7}, number = {5}, pages = {e37678}, publisher = {Public Library of Science}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Costa, Tiago RD; Amer, Ayad AA; Fällman, Maria; Fahlgren, Anna; Francis, Matthew S Coiled-coils in the YopD translocator family: A predicted structure unique to the YopD N-terminus contributes to full virulence of Yersinia pseudotuberculosis Journal Article Infection, Genetics and Evolution, 12 (8), pp. 1729–1742, 2012. @article{costa2012coiled, title = {Coiled-coils in the YopD translocator family: A predicted structure unique to the YopD N-terminus contributes to full virulence of Yersinia pseudotuberculosis}, author = {Tiago RD Costa and Ayad AA Amer and Maria Fällman and Anna Fahlgren and Matthew S Francis}, year = {2012}, date = {2012-01-01}, journal = {Infection, Genetics and Evolution}, volume = {12}, number = {8}, pages = {1729--1742}, publisher = {Elsevier}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Westermark, Linda; Fahlgren, Anna; Fällman, Maria Immune response to diphtheria toxin-mediated depletion complicates the use of the CD11c-DTRtg model for studies of bacterial gastrointestinal infections Journal Article Microbial pathogenesis, 53 (3-4), pp. 154–161, 2012. @article{westermark2012immune, title = {Immune response to diphtheria toxin-mediated depletion complicates the use of the CD11c-DTRtg model for studies of bacterial gastrointestinal infections}, author = {Linda Westermark and Anna Fahlgren and Maria Fällman}, year = {2012}, date = {2012-01-01}, journal = {Microbial pathogenesis}, volume = {53}, number = {3-4}, pages = {154--161}, publisher = {Elsevier}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Thorslund, Sara E; Edgren, Tomas; Pettersson, Jonas; Nordfelth, Roland; Sellin, Mikael E; Ivanova, Ekaterina; Francis, Matthew S; Isaksson, Elin L; Wolf-Watz, Hans; Fällman, Maria The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function Journal Article PloS one, 6 (2), pp. e16784, 2011. @article{thorslund2011rack1, title = {The RACK1 signaling scaffold protein selectively interacts with Yersinia pseudotuberculosis virulence function}, author = {Sara E Thorslund and Tomas Edgren and Jonas Pettersson and Roland Nordfelth and Mikael E Sellin and Ekaterina Ivanova and Matthew S Francis and Elin L Isaksson and Hans Wolf-Watz and Maria Fällman}, year = {2011}, date = {2011-01-01}, journal = {PloS one}, volume = {6}, number = {2}, pages = {e16784}, publisher = {Public Library of Science}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Fahlgren, Anna; Westermark, Linda; Akopyan, Karen; Fällman, Maria Cell type-specific effects of Yersinia pseudotuberculosis virulence effectors Journal Article Cellular microbiology, 11 (12), pp. 1750–1767, 2009. @article{fahlgren2009cell, title = {Cell type-specific effects of Yersinia pseudotuberculosis virulence effectors}, author = {Anna Fahlgren and Linda Westermark and Karen Akopyan and Maria Fällman}, year = {2009}, date = {2009-01-01}, journal = {Cellular microbiology}, volume = {11}, number = {12}, pages = {1750--1767}, publisher = {Wiley Online Library}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Kouokam, Clavin J; Wai, Sun Nyunt; Fällman, Maria; Dobrindt, Ulrich; Hacker, Jörg; Uhlin, Bernt Eric Active cytotoxic necrotizing factor 1 associated with outer membrane vesicles from uropathogenic Escherichia coli Journal Article Infection and immunity, 74 (4), pp. 2022–2030, 2006. @article{kouokam2006active, title = {Active cytotoxic necrotizing factor 1 associated with outer membrane vesicles from uropathogenic Escherichia coli}, author = {Clavin J Kouokam and Sun Nyunt Wai and Maria Fällman and Ulrich Dobrindt and Jörg Hacker and Bernt Eric Uhlin}, year = {2006}, date = {2006-01-01}, journal = {Infection and immunity}, volume = {74}, number = {4}, pages = {2022--2030}, publisher = {Am Soc Microbiol}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Deleuil, Fabienne; Mogemark, Lena; Francis, Matthew S; Wolf-Watz, Hans; Fällman, Maria Interaction between the Yersinia protein tyrosine phosphatase YopH and eukaryotic Cas/Fyb is an important virulence mechanism Journal Article Cellular microbiology, 5 (1), pp. 53–64, 2003. @article{deleuil2003interaction, title = {Interaction between the Yersinia protein tyrosine phosphatase YopH and eukaryotic Cas/Fyb is an important virulence mechanism}, author = {Fabienne Deleuil and Lena Mogemark and Matthew S Francis and Hans Wolf-Watz and Maria Fällman}, year = {2003}, date = {2003-01-01}, journal = {Cellular microbiology}, volume = {5}, number = {1}, pages = {53--64}, publisher = {Wiley Online Library}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Hamid, Nivia; Gustavsson, Anna; Andersson, Kerstin; McGee, Karen; Persson, Cathrine; Rudd, Christopher E; Fällman, Maria YopH dephosphorylates Cas and Fyn-binding protein in macrophages Journal Article Microbial pathogenesis, 27 (4), pp. 231–242, 1999. @article{hamid1999yoph, title = {YopH dephosphorylates Cas and Fyn-binding protein in macrophages}, author = {Nivia Hamid and Anna Gustavsson and Kerstin Andersson and Karen McGee and Cathrine Persson and Christopher E Rudd and Maria Fällman}, year = {1999}, date = {1999-01-01}, journal = {Microbial pathogenesis}, volume = {27}, number = {4}, pages = {231--242}, publisher = {Elsevier}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Persson, Cathrine; Nordfelth, Roland; Andersson, Kerstin; Forsberg, Åke; Wolf-Watz, Hans; Fällman, Maria Localization of the Yersinia PTPase to focal complexes is an important virulence mechanism Journal Article Molecular microbiology, 33 (4), pp. 828–838, 1999. @article{persson1999localization, title = {Localization of the Yersinia PTPase to focal complexes is an important virulence mechanism}, author = {Cathrine Persson and Roland Nordfelth and Kerstin Andersson and Åke Forsberg and Hans Wolf-Watz and Maria Fällman}, year = {1999}, date = {1999-01-01}, journal = {Molecular microbiology}, volume = {33}, number = {4}, pages = {828--838}, publisher = {Wiley Online Library}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Andersson, Kerstin; Magnusson, Karl-Eric; Majeed, Meytham; Stendahl, Olle; Fällman, Maria Yersinia pseudotuberculosis-induced calcium signaling in neutrophils is blocked by the virulence effector YopH Journal Article Infection and immunity, 67 (5), pp. 2567–2574, 1999. @article{andersson1999yersinia, title = {Yersinia pseudotuberculosis-induced calcium signaling in neutrophils is blocked by the virulence effector YopH}, author = {Kerstin Andersson and Karl-Eric Magnusson and Meytham Majeed and Olle Stendahl and Maria Fällman}, year = {1999}, date = {1999-01-01}, journal = {Infection and immunity}, volume = {67}, number = {5}, pages = {2567--2574}, publisher = {Am Soc Microbiol}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Persson, Cathrine; Carballeira, Nivia; Wolf-Watz, Hans; Fällman, Maria The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions Journal Article The EMBO journal, 16 (9), pp. 2307–2318, 1997. @article{persson1997ptpase, title = {The PTPase YopH inhibits uptake of Yersinia, tyrosine phosphorylation of p130Cas and FAK, and the associated accumulation of these proteins in peripheral focal adhesions}, author = {Cathrine Persson and Nivia Carballeira and Hans Wolf-Watz and Maria Fällman}, year = {1997}, date = {1997-01-01}, journal = {The EMBO journal}, volume = {16}, number = {9}, pages = {2307--2318}, publisher = {John Wiley & Sons, Ltd}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Holmström, Anna; Pettersson, Jonas; Rosqvist, Roland; Håkansson, Sebastian; Tafazoli, Farideh; Fällman, Maria; Magnusson, Karl-Eric; Wolf-Watz, Hans; Forsberg, Åke YopK of Yersinia pseudotuberculosis controls translocation of Yop effectors across the eukaryotic cell membrane Journal Article Molecular microbiology, 24 (1), pp. 73–91, 1997. @article{holmstrom1997yopk, title = {YopK of Yersinia pseudotuberculosis controls translocation of Yop effectors across the eukaryotic cell membrane}, author = {Anna Holmström and Jonas Pettersson and Roland Rosqvist and Sebastian Håkansson and Farideh Tafazoli and Maria Fällman and Karl-Eric Magnusson and Hans Wolf-Watz and Åke Forsberg}, year = {1997}, date = {1997-01-01}, journal = {Molecular microbiology}, volume = {24}, number = {1}, pages = {73--91}, publisher = {Wiley Online Library}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Andersson, Kerstin; Carballeira, Nivia; Magnusson, Karl-Eric; Persson, Cathrine; Stendahl, Olle; Wolf-Watz, Hans; Fällman, Maria YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signalling associated with phagocytosis Journal Article Molecular microbiology, 20 (5), pp. 1057–1069, 1996. @article{andersson1996yoph, title = {YopH of Yersinia pseudotuberculosis interrupts early phosphotyrosine signalling associated with phagocytosis}, author = {Kerstin Andersson and Nivia Carballeira and Karl-Eric Magnusson and Cathrine Persson and Olle Stendahl and Hans Wolf-Watz and Maria Fällman}, year = {1996}, date = {1996-01-01}, journal = {Molecular microbiology}, volume = {20}, number = {5}, pages = {1057--1069}, publisher = {Wiley Online Library}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Fällman, MARIA; Andersson, Kerstin; Håkansson, SEBASTIAN; Magnusson, Karl-Eric; Stendahl, Olle; Wolf-Watz, Hans Yersinia pseudotuberculosis inhibits Fc receptor-mediated phagocytosis in J774 cells. Journal Article Infection and immunity, 63 (8), pp. 3117–3124, 1995. @article{fallman1995yersinia, title = {Yersinia pseudotuberculosis inhibits Fc receptor-mediated phagocytosis in J774 cells.}, author = {MARIA Fällman and Kerstin Andersson and SEBASTIAN Håkansson and Karl-Eric Magnusson and Olle Stendahl and Hans Wolf-Watz}, year = {1995}, date = {1995-01-01}, journal = {Infection and immunity}, volume = {63}, number = {8}, pages = {3117--3124}, publisher = {Am Soc Microbiol}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Särndahl, Eva; Lindroth, Margaretha; Bengtsson, Torbjörn; Fällman, Maria; Gustavsson, Johanna; Stendahl, Olle; Andersson, Tommy Association of ligand-receptor complexes with actin filaments in human neutrophils: a possible regulatory role for a G-protein. Journal Article The Journal of cell biology, 109 (6), pp. 2791–2799, 1989. @article{sarndahl1989association, title = {Association of ligand-receptor complexes with actin filaments in human neutrophils: a possible regulatory role for a G-protein.}, author = {Eva Särndahl and Margaretha Lindroth and Torbjörn Bengtsson and Maria Fällman and Johanna Gustavsson and Olle Stendahl and Tommy Andersson}, year = {1989}, date = {1989-01-01}, journal = {The Journal of cell biology}, volume = {109}, number = {6}, pages = {2791--2799}, keywords = {}, pubstate = {published}, tppubtype = {article} } |
Maria Fällman is a professor in Medical microbiology at Umeå University´s Department of Molecular Biology and an Icelab Affiliate. She performed her undergraduate studies in Molecular Biology at Umeå University and her PhD studies at University of Linköping, she was recruited to Umeå University as Forskarassistent in 1996.
The research in the FallmanLab aims at understanding molecular mechanisms behind the ability of bacteria to adapt to different environments. Current work involves studies of bacterial adaption mechanisms of importance for maintenance of infection using transcriptomic analyses combined with classical molecular biology methods. The group has been involved in developing advanced methods for RNA extraction and in vivo gene expression analyses. The work includes experimental systems with chronic mouse infections of model bacteria such as Yersinia pseudotuberculosis and Salmonella Typhimurium as well as analysis of in vivo bacterial gene expression of bacteria from human patient samples. Data analyses are now expanded to include system biology and machine learning, approaches for cross microbial comparisons in this Icelab connected project.
Current Projects
New targets for future antimicrobials (Kempe foundation Icelab)
M Fallman, K. Avican, M Rosvall, J. Normark
Molecular mechanisms of critical importance for establishment and persistence of gastrointestinal infections (VR-MH)
M. Fallman
New in vivo adapted approaches to reveal molecular mechanisms of bacterial persistence (KAW project 2016.0063)
M Fallman Umu, M Sellin Uu, M Rhen KI
Regulation of Type Three Secretion in Yersinia pseudotuberculosis
R. Navais, H. Wolf-Watz
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